Faculty of Medicine, Dentistry and Health Sciences Department of Microbiology and Immunology

Jackson Laboratory

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Include: Research Interests | Major Research Projects | Laboratory Staff | Recent Publications

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Dr. David Jackson's Home Page

Research Interests

 

Major Research Projects

 

Laboratory Staff

 

Recent Publications: 2007 - Present

List of Publications prior to 2007

  1. Chua B, Eriksson EMY, Brown L, Zeng W, Gowans E, Torresi J, Jackson D. A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection. Vaccine 2008; 26: 4866-4875.
  2. Baz A, Buttigieg K, Zeng W, Rizkalla M, Jackson D, Groves P, Kelso A. Branched and linear lipopeptide vaccines have different effects on primary CD4+ and CD8+ T-cell activation but induce similar tumor-protective memory CD8+ T-cell responses. Vaccine 2008; 26: 2570-2579.
  3. Chua B, Eriksson EMY, Poole D, Zeng W, Jackson D. Dendritic cell acquisition of epitope cargo mediated by simple cationic peptide structures. Peptides 2008; 29: 881-890.
  4. Thammanichanond D, Moneer S, Yotnda P, Aitken C, Earnest-Silveira L, Jackson D, Hellard M, McCluskey J, Torresi J, Bharadwaj M. Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response. Clinical Immunology 2008; 128: 329-339.
  5. Jones KL, Brown L, Eriksson EMY, French RA, Latour PA, Loveland BE, Wall DM, Roberts SK, Jackson D, Gowans EJ. Human dendritic cells pulsed with specific lipopeptides stimulate autologous antigen-specific T cells without the addition of exogenous maturation factors. Journal of Viral Hepatitis 2008; 15: 761-772.
  6. Alphs H, Gambhira R, Karanam B, Roberts J, Jagu S, Schiller J, Zeng W, Jackson D, Roden R. Protection against heterologous human papillomavirus challenge by a synthetic lipopeptide vaccine containing a broadly cross-neutralizing epitope of L2. Proc Nat Acad Sci USA 2008; 105: 5850-5855.
  7. Chua B, Zeng W, Jackson D. Synthesis of Toll-Like Receptor-2 Targeting Lipopeptides as Self-Adjuvanting Vaccines. Methods in Molecular Biology 2008; 494: 247-61.
  8. Brown L, Deliyannis G, Kedzierska K, Lau YF, Ng WC, Zeng W, Gilbertson B, Lim B, Cobbin JCA, Jackson D, Turner S, Kelso A. Lipopeptide Vaccines Illustrate the Potential Role of Subtype-Crossreactive T Cell Responses in the Control of Seasonal and Pandemic Influenza. In: Options for the Control of Influenza VI, International Medical Press (London). 2008; 199-201.
  9. Day EB, Zeng W, Doherty P, Jackson D, Kedzierska K, Turner S. The context of epitope presentation can influence functional quality of recalled Influenza A virus-specific memory CD8+ T cells. Journal of Immunology 2007; 179: 2187-2194.
  10. Torresi J, Stock OM, Fischer AE, Grollo L, Drummer H, Boo I, Zeng W, Earnest-Silveira L, Jackson D. A self-adjuvanting multiepitope immunogen that induces a broadly cross-reactive antibody to Hepatitis C virus. Hepatology 2007; 45: 911-920.
  11. Yang X, Adda G, Keizer D, Murphy J, Rizkalla M, Perugini M, Jackson D, Anders RF, Norton RS. A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils. Journal of Peptide Science 2007; 13: 839-48.
  12. Chua BYL, Zeng W, Lau YF, Jackson D. Comparison of lipopeptide-based immunocontraceptive vaccines containing different lipid groups. Vaccine 2007; 25: 92-101.
  13. Torresi J, Fischer AE, Grollo L, Zeng W, Drummer H, Jackson D. Induction of neutralizing antibody responses to hepatitis C virus with synthetic peptide constructs incorporating both antibody and T-helper epitopes. Immunology and Cell Biology 2007; 85: 169-73.
  14. Eriksson EMY, Jackson D. Recent Advances with TLR2-Targeting Lipopeptide-Based Vaccines. Current Protein and Peptide Science 2007; 8: 412-417.
  15. Clements A, Tull D, Jenney A, Gabbe J, Kim S-H, Bishop R, McPhee J, Hancock R, Hartland E, Strugnell R, McConville M, Jackson D, Wijburg O, Pearse M. Secondary acylation of Klebsiella pneumoniae lipopolysaccharide contributes to sensitivity to antibacterial peptides. Journal of Biological Chemistry 2007; 282: 15569-15577.
  16. Chua BYL, Zeng W, Jackson D. Simple branched arginine-based structures can enhance the cellular uptake of peptide cargos. International Journal of Peptide Research and Therapeutics 2007; 13; 431-437.
  17. Dudek N, Maier S, Chen Z, Mudd P, Mannering S, Jackson D, Zeng W, Keech C, Hamlin K, Farris A, McCluskey J, Bachmann M, Workman-Azbill J, Davis-Schwarz K, Pan Z. T cell epitopes of the La/SSB autoantigen in humanized transgenic mice expressing the HLA class II haplotype DRB1*0301/DQB1*0201. Arthritis and Rheumatism 2007; 56: 3387-3398.
  18. Zeng W, Pagnon J, Jackson D. The C-terminal pentapeptide of LHRH is a dominant B cell epitope with antigenic and biological function. Molecular Immunology 2007; 44: 3724-3731.
  19. Walker J, Ghosh S, Pagnon J, Colantoni C, Newbold A, Zeng W, Jackson D. Totally synthetic peptide-based immunocontraceptive vaccines show activity in dogs of different breeds. Vaccine 2007; 25: 7111-7119.

 

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