Projects

HLA Msat Working Group

As microsatellites are still quite useful markers of the MHC region we propose to continue such a systematic work within a working group interested in those MHC markers. The Msat working group on HLA region Msat would have as main objective to organise the tracking and sharing of information regarding various aspects of HLA – Msat; it could be organized in various branches: techniques; nomenclature; mapping; polymorphism information; population frequencies and linkage disequilibrium; disease studies; transplantation studies; miscellaneous. The outcome could be a common database of information with the following aims:

to update an integrated map of HLA region genes and markers for the Msat data;
to continue completing the Msat lists and characteristics (as in ref Foissac et al (1997,1998, 2000), and in Cullen et al, 2003, but potentially including other parameters that should be agreed upon and organised in a database;
to get population frequencies on Msat available in a common web accessible resource (for example the HLA region allele frequency database proposed by Derek Middleton (Northern Ireland) :allelefrequencies.net, but there may be other ideas?)
to provide electronically available forms for people submitting their data for the database in a standardized format from their computer;
to get these regularly updated versions available through Internet, possibly as initiated by NCBI (http://www.ncbi.nlm.nih.gov/mhc/html/STRsearch2.html) and with links to relevant literature references and updates being mentioned in MHC specialized literature (agreement with one or several journal to be searched for : Tissue Antigens? Immunogenetics? Other?).

Update: August, 2004

MSat Working Group Participation Form

HLA Microsatellite Working Group Meeting, Toulouse, June 30 - July 1, 2005

Project chair: Anne Cambon-Thomsen

Contact: Pierre-Antoine Gourraud

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